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their biological effects and potential molecular targets
3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid isolated from roots of Platycodon grandiflorum
The Pyrido[b]indole MDM2 Inhibitor SP-141 Exerts Potent Therapeutic Effects in Breast Cancer Models
Chemical Name: N-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-5-({6-[(methylamino)methyl]pyrimidin-4-yl}oxy)-1H-indole-1-carboxamide
A-366 is also a potent
EGFR-IN-1 14 mesylate their biological effects and potentialEGFR IN 1 (compound 24) is an orally active and irreversible L858R T790M mutant selective EGFR inhibitor. EGFR IN 1 potently inhibits Gefitinib resistant EGFR L858R, T790M with 100 fold selectivity over wild type EGFR. EGFR IN 1 displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. Product information CAS Number: 1625677 63 5 Molecular Weight: 514. 58 Formula: C28H30N6O4 Chemical
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