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Formula: C24H16F3NO4
2018 Dec 21
PI3K/mTOR kinase inhibitor GDC-0980 inhibits both PI3K kinase and mTOR kinase
The protection of omtriptolide against AKI is associated with a decrease in p-ERK and is independent of MKP-1 and proinflammatory cytokines
RITA (1 μM) stabilizes p53 by inhibiting p53/E6AP interaction
(Rac)-Calpain Inhibitor XII inib bromide Formula: C24H16F3NO4(Rac) Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I ( calpain, Ki=19 nM). (Rac) Calpain Inhibitor XII has lower affinities for calpain II (m calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac) Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Product information CAS Number: 181769 57 3