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Biggadike K
Isoamyl 4-methoxycinnamate
SR9243 induces cell death in multiple types of cancer and does not cause the side effects that have derailed previous attempts to target these processes
PubMed PMID: 24179414
RhoA inhibitor (GGTI298 Trifluoroacetate) significantly reduces cAMP agonist-stimulated apical K+ conductance
ETP-46321 Size:Solid 10 mg Biggadike KETP 46321 is a potent and orally bioavailable PI3K , inhibitor with potent biochemical and cellular activity and good pharmacokinetic properties (PK) after oral dosing. ETP 46321 PK PD studies showed time dependent downregulation of AKT(Ser473) phosphorylation, which correlates with compound levels in tumor tissue and demonstrating to be efficacious in a GEMM mouse tumor model driven by a K Ras(G12V) oncogenic mutation. Treatment with ETP 46321
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US$ 825.00