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3-dihydrobenzo(b)(1
Chemical Name: 3-((6-(4
LCZ696 could inhibit the expression of ANP
Smiles: C[N+](C)(C)CC([O-])=O
InChiKey: IHIUGIVXARLYHP-UXNJHFGPSA-N
RAF265 enafil dihydrochloride 3-dihydrobenzo(b)(1CHIR 265 is an orally bioavailable small molecule with potential antineoplastic activity. CHIR 265 binds and inhibits Raf kinases, which may result in a reduction of tumor cell growth and proliferation, and tumor cell death. In addition, this agent inhibits vascular endothelial growth factor receptor type 2 (VEGFR 2), thereby disrupting tumor angiogenesis. Raf kinases are critical enzymes in the Ras Raf MEK ERK signaling pathway and are frequently