and orally active LPA(1) receptor antagonist which inhibits lung fibrosis in the mouse bleomycin model
and FGFR3-dependent BaF3 cells with IC50 values which are in the low nanomolar range and comparable to those observed for the inhibition of the receptors kinase activity in the enzymatic assay
InChi: InChI=1S/C19H13Cl2N3O2S/c20-12-5-1-10(2-6-12)14-9-15(11-3-7-13(21)8-4-11)24-19(14)16(25)22-18(27)23-17(19)26/h1-8
InChiKey: ARFHIAQFJWUCFH-IZZDOVSWSA-N
Solubility: DMSO : 25 mg/mL (106
L-Allothreonine Size:Contact [email protected] for quotation and orally active LPA(1) receptorL Allothreonine (H allo Thr OH) is an endogenous metabolite. Product information CAS Number: 28954 12 3 Molecular Weight: 119. 12 Formula: C4H9NO3 Chemical Name: (2S,3S) 2 amino 3 hydroxybutanoic acid Smiles: C[C@H](O)[C@H](N)C(O)=O InChiKey: AYFVYJQAPQTCCC HRFVKAFMSA N InChi: InChI=1S C4H9NO3 c1 2(6)3(5)4(7)8 h2 3,6H,5H2,1H3,(H,7,8) t2 ,3 m0 s1 Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis) Solubility: