Cbz-NH-PEG2-CH2COOH ethyl-PEG4-propargyl ONX-0914 was dosed to mice

ONX-0914 was dosed to mice by either intravenous or subcutaneous administration at 2-10 mg/kg once a day for 5 days

Formula: C23H40N2O7

R)-sulfoximine (BSO: 50 μM) treatment for 48 hr results in a 95% decrease in ZAZ and M14 melanoma cell line GSH levels

Perflubron (1-Bromoheptadecafluorooctane

InChiKey: ZGGHKIMDNBDHJB-WPPSXBOFSA-M

Cbz-NH-PEG2-CH2COOH ethyl-PEG4-propargyl ONX-0914 was dosed to miceCbz NH PEG2 CH2COOH is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 165454 06 8 Molecular Weight: 297. 30 Formula: C14H19NO6 Chemical Name: 2 [2 (2 {[(benzyloxy)carbonyl]amino}ethoxy)ethoxy]acetic acid Smiles: OC(=O)COCCOCCNC(=O)OCC1C=CC=CC=1 InChiKey: GWUWSVXMAZFFNT UHFFFAOYSA N InChi: InChI=1S C14H19NO6 c16 13(17)11 20 9 8 19 7 6 15 14(18)21 10 12 4 2 1 3 5 12 h1 5H,6 11H2,(H,15,18)(H,16,17)