Bazedoxifene - CAS# 198481-32-2 t A Stat5 and Erk1/2 in R10

Stat5 and Erk1/2 in R10 cells

CAS Number: 62893-19-0

Formula: C27H22Cl2N4O

30 minutes) exhibits porcine gastric H+

InChi: InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H

Bazedoxifene - CAS# 198481-32-2 t A Stat5 and Erk1/2 in R10Bazedoxifene, also known as WAY 140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole based ER ligand that binds to both ER (IC50 = 26 nM) and ER (IC50 = 99