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exhibits species-specific activity and acts as a negative allosteric modulator of human P2X7 (pIC50 = 6
iron metabolism proteins
Exatecan Mesylate (34 nM) stabilizes DNA-TopoI complexes in PC-6 and PC-6/SN2-5 cells
Epub 2012 Oct 24
This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs
Proparacaine Hydrochloride - CAS# 5875-06-9 cylate exhibits species-specific activity and actsProparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. It is used as a topical ophthalmic anesthetic. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.
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