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RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 InChiKey: NBMBIEOUVBHEBM-UHFFFAOYSA-N

SKU: 95108891985

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Description

InChiKey: NBMBIEOUVBHEBM-UHFFFAOYSA-N

Smiles: ONC(=O)CCCCCCC(=O)NC1C=CC=CC=1

Clotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections

resulting in hemorrhagic necrosis and a decrease in angiogenesis

It inhibits KDM2A at IC50 ~1

RX-3117 - CAS# 865838-26-2 Catalog No.:M11354-10 InChiKey: NBMBIEOUVBHEBM-UHFFFAOYSA-NRX 3117, also known as TV 1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX 3117 is taken up by cells through a carrier mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX DP) and triphosphate forms (RX TP). The triphosphate form is incorporated into

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